The point here is that it's not that B.1.1.7, B.1.351 and P.1 have unique mutations not present in other circulating viruses, it's that these VOC lineages have acquired some of the most extensive suites of spike S1 mutations seen in circulating viruses. 7/15 pic.twitter.com/bwnOGNToRs

— Trevor Bedford (@trvrb) April 14, 2021