They are black magic. When I had to start managing a fleet of boats with modern big outboards, we started budgeting more money for professional maintenance/repair and less for training of staff to do that. The key was identifying several good shops and developing good relationships with them.
Haven't used a cat like yours, but trim on every outboard- and I/O-powered motorboat (up to about 35 ft) I've used depends on load, speed, and sea state. Planing boats at speed I trim bow up until porpoising starts then down a touch.